Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 2/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052318 | 1.00 | ALDH1A1 (0.70) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL7456837 | 0.81 | MAOB (0.73) | KIF11PRKCZMAOA | |
| SCHEMBL23052415 | 0.74 | LMNA (1.00) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL23052466 | 0.74 | LMNA (1.00) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL25274761 | 0.73 | KIF11 (0.53) | ALDH1A1KDM4ESMN1; SMN2HPGDRAB9A | |
| SCHEMBL7461031 | 0.73 | MAOB (0.73) | KIF11MAOA | |
| SCHEMBL27276968 | 0.72 | KIF11 (0.74) | MAPTKIF11MAOA | |
| SCHEMBL3315221 | 0.71 | RAB9A (0.78) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL22633772 | 0.70 | ALDH1A1 (0.81) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL30751943 | 0.69 | MAOA (0.74) | KMT2AMEN1RAB9ANPC1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |