Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 2/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25232491 | 1.00 | PRKAG1 (0.49) | PRKAG1PRKAA1PRKAB1TDO2MGLL | |
| SCHEMBL25276617 | 0.86 | PRKAG1 (0.46) | PRKAG1PRKAA1PRKAB1TDO2MEN1 | |
| SCHEMBL31055692 | 0.86 | PRKAG1 (0.46) | PRKAG1PRKAA1PRKAB1TDO2MEN1 | |
| SCHEMBL25233661 | 0.82 | MGLL (0.48) | PRKAG1PRKAA1PRKAB1MGLLMEN1 | |
| SCHEMBL25227613 | 0.77 | MGLL (0.41) | PRKAG1PRKAA1PRKAB1MGLLPDE3B | |
| SCHEMBL25281510 | 0.72 | CNR1 (0.43) | PDE3BPDE3A | |
| SCHEMBL25234821 | 0.70 | SCN9A (0.48) | — | |
| SCHEMBL31055662 | 0.70 | SCN9A (0.48) | — | |
| SCHEMBL29746274 | 0.69 | SLC6A3 (0.50) | MEN1KMT2A | |
| SCHEMBL25233707 | 0.68 | MGLL (0.41) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110958-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-06-22 | — | — | WO | disclosed |