SCHEMBL2528017

SCHEMBL2528017

C=C(C)C(=O)OC(C(C)C)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.39
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19050438 0.82 TSHR (0.34) TSHRALDH1A1
SCHEMBL8641579 0.76 ALOX15 (0.32)
SCHEMBL143424 0.76 ALDH1A1 (0.44) TSHRALDH1A1THRB
SCHEMBL771313 0.76 ALDH1A1 (0.44) TSHRALDH1A1THRB
SCHEMBL31364544 0.76 ALDH1A1 (0.44) TSHRALDH1A1THRB
SCHEMBL771097 0.76 ALDH1A1 (0.44) TSHRALDH1A1THRB
SCHEMBL674950 0.75 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL8022199 0.75 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL31364542 0.75 ALDH1A1 (0.48) TSHRALDH1A1THRB
SCHEMBL10899304 0.75 ALDH1A1 (0.48) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2577361-B1 ANTIREFLECTIVE COATING COMPOSITION AND PROCESS FOR MANUFACTURING MICROELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2016-10-12 EP disclosed
US-9315636-B2 Stable metal compounds, their compositions and methods AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-04-19 US disclosed
US-9170494-B2 Antireflective compositions and methods of using same AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2015-10-27 US disclosed
US-20140159278-A1 STABLE METAL COMPOUNDS, THEIR COMPOSITIONS AND METHODS AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2014-06-12 US disclosed
EP-2723809-A1 AN UNDERLAYER COMPOSITION AND PROCESS THEREOF AZ Electronic Materials USA Corp. (US) 2014-04-30 EP disclosed
US-20130337379-A1 ANTIREFLECTIVE COMPOSITIONS AND METHODS OF USING SAME AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2013-12-19 US disclosed
US-8568958-B2 Underlayer composition and process thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-10-29 US disclosed
US-8445181-B2 Antireflective coating composition and process thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-05-21 US disclosed
EP-2577361-A1 ANTIREFLECTIVE COATING COMPOSITION AND PROCESS FOR MANUFACTURING MICROELECTRONIC DEVICE AZ Electronic Materials USA Corp. (US) 2013-04-10 EP disclosed
WO-2012176043-A1 AN UNDERLAYER COMPOSITION AND PROCESS THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-27 WO disclosed
US-20120328990-A1 UNDERLAYER COMPOSITION AND PROCESS THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-27 US disclosed
US-20110300488-A1 Antireflective Coating Composition and Process Thereof MERCK PATENT GMBH (DE) 2011-12-08 US disclosed
US-8039201-B2 Antireflective coating composition and process thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2011-10-18 US disclosed
WO-2009066169-A1 AN ANTIREFLECTIVE COATING COMPOSITION AND PROCESS THEREOF AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-05-28 WO disclosed
US-20090130591-A1 Antireflective Coating Composition and Process Thereof MERCK PATENT GMBH (DE) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140159278-A1 STABLE METAL COMPOUNDS, THEIR COMPOSITIONS AND METHODS SOD1, SOD3, SLC30A6 TSHR 4274/4885ALDH1A1 3279/4885THRB 4802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.