Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104896 | 0.75 | GAA (0.34) | METGAALMNACYP2C19CYP1A2 | |
| SCHEMBL25274680 | 0.75 | PKM (0.41) | GAALMNAMAPTKDM4EMEN1 | |
| SCHEMBL10196841 | 0.72 | GAA (0.40) | GAALMNAMAPTKDM4EMEN1 | |
| SCHEMBL9362665 | 0.72 | HRH3 (0.36) | GAALMNACYP2C19CYP1A2MAPT | |
| SCHEMBL8149332 | 0.71 | MAPT (0.36) | GAALMNACYP2C19CYP1A2MAPT | |
| SCHEMBL17723466 | 0.71 | PTGS2 (0.36) | GAALMNACYP2C19CYP1A2MAPT | |
| SCHEMBL12877231 | 0.71 | TSHR (0.37) | GAAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL24246974 | 0.69 | HRH3 (0.37) | GAALMNACYP2C19MAPTKDM4E | |
| SCHEMBL21384024 | 0.68 | MARS1 (0.43) | GAALMNACYP1A2MAPTKDM4E | |
| SCHEMBL1257313 | 0.67 | PTGS2 (0.38) | LMNACYP2C19CYP1A2PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049033-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-13 | — | — | US | claimed |
| US-20250042875-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-06 | — | — | US | claimed |
| CN-118891256-A | Pesticidal activity pyridazinone compounds of (A) | 先正达农作物保护股份公司 | 2024-11-01 | — | — | CN | claimed |
| EP-4444712-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2024-10-16 | — | — | EP | claimed |
| EP-4423077-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2024-09-04 | — | — | EP | claimed |
| CN-118265707-A | Pesticidally active pyridazinone compounds | 先正达农作物保护股份公司 | 2024-06-28 | — | — | CN | claimed |
| WO-2023104714-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-15 | — | — | WO | claimed |
| WO-2023072849-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-04 | — | — | WO | claimed |
| US-20250049033-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-13 | — | — | US | disclosed |
| US-20250042875-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-06 | — | — | US | disclosed |
| CN-118891256-A | Pesticidal activity pyridazinone compounds of (A) | 先正达农作物保护股份公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-4444712-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2024-10-16 | — | — | EP | disclosed |
| EP-4423077-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2024-09-04 | — | — | EP | disclosed |
| CN-118265707-A | Pesticidally active pyridazinone compounds | 先正达农作物保护股份公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2023104714-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023072849-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049033-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | CYP4B1, ACHE, NQO2 | MET 4707/4885GAA 3120/4885LMNA 1323/4885 |
| US-20250042875-A1 | PESTICIDALLY ACTIVE PYRIDAZINONE COMPOUNDS | ACHE, PNPO, DDT | MET 4215/4885GAA 3289/4885LMNA 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.