SCHEMBL2528672

SCHEMBL2528672

[c]1c(-c2ccccn2)ccc2cc3ccccc3cc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.42
LMNA P02545 6/20 0.42
CCR1 P32246 3/20 0.42
CCR5 P51681 3/20 0.42
CCR8 P51685 3/20 0.42
CYP1A2 P05177 2/20 0.42
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.42
BLM P54132 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42
P4HTM Q9NXG6 1/20 0.42
SMN1; SMN2 Q16637 6/20 0.41
TP53 P04637 5/20 0.41
ALOX15 P16050 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
HTT P42858 2/20 0.41
ALPL P05186 1/20 0.41
HSP90AA1 P07900 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4276024 0.84 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4718441 0.83 CYP3A4 (0.33) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4720568 0.83 METAP2 (0.37) KDM4ESMN1; SMN2TP53MAPTALDH1A1
SCHEMBL4723454 0.81 HTR2C (0.35)
SCHEMBL18317760 0.78 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4723581 0.78
SCHEMBL4722546 0.77 RAB9A (0.42) KDM4ELMNACYP1A2BLMSMN1; SMN2
SCHEMBL18317478 0.76 HPRT1 (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4719352 0.74 NPC1 (0.38) KDM4ECYP1A2SMN1; SMN2MAPTNPC1
SCHEMBL4723166 0.74 HAO1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024111206-A1 ORGANIC ELECTRONIC ELEMENT AND COMPOUND 東ソー株式会社 2024-05-30 WO disclosed
WO-2024105964-A1 ORGANIC ELECTRONIC ELEMENT AND COMPOUND 東ソー株式会社 2024-05-23 WO disclosed
US-9812652-B2 Cyclic azine compound having adamantyl group, production method, and organic electroluminescent device containing it as constituent component TOSOH CORPORATION (JP) 2017-11-07 US disclosed
US-20160372678-A1 CYCLIC AZINE COMPOUND HAVING ADAMANTYL GROUP, PRODUCTION METHOD, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING IT AS CONSTITUENT COMPONENT TOSOH CORPORATION (JP) 2016-12-22 US disclosed
US-8445120-B2 Triphenylene based aromatic compounds and OLEDs utilizing the same NATIONAL TSING HUA UNIVERSITY (TW) 2013-05-21 US disclosed
US-8288015-B2 Triphenylene based aromatic compounds and OLEDs utilizing the same NATIONAL TSING HUA UNIVERSITY (TW) 2012-10-16 US disclosed
US-20120248429-A1 TRIPHENYLENE BASED AROMATIC COMPOUNDS AND OLEDS UTILIZING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2012-10-04 US disclosed
US-20110254436-A1 TRIPHENYLENE BASED AROMATIC COMPOUNDS AND OLEDS UTILIZING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2011-10-20 US disclosed
US-20080200475-A1 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors PFIZER INC. 2008-08-21 US disclosed
US-20080194590-A1 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors PFIZER INC 2008-08-14 US disclosed
EP-1896483-A2 4-PIPERAZINYLTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS Pharmacia & Upjohn Company LLC (US) 2008-03-12 EP disclosed
EP-1874780-A1 4-PIPERAZINYLTHIENO[2,3-D]PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS Pharmacia & Upjohn Company LLC (US) 2008-01-09 EP disclosed
EP-1869051-A1 4-PIPERAZINYLTHIENO Ý2,3-D¨PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS Pharmacia & Upjohn Company LLC (US) 2007-12-26 EP disclosed
EP-1866317-A1 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS Pharmacia & Upjohn Company LLC (US) 2007-12-19 EP disclosed
EP-1844052-A1 THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION Pharmacia & Upjohn Company LLC (US) 2007-10-17 EP disclosed
WO-2006103544-A2 4-PIPERAZINYLTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-10-05 WO disclosed
WO-2006103545-A1 4-PIPERAZINYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-10-05 WO disclosed
WO-2006103555-A1 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-10-05 WO disclosed
WO-2006100591-A1 4-PIPERAZINNYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-09-28 WO disclosed
WO-2006079916-A1 THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION PHARMACIA & UPJOHN COMPANY LLC (US) 2006-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110254436-A1 TRIPHENYLENE BASED AROMATIC COMPOUNDS AND OLEDS UTILIZING THE SAME OCIAD1, TYR, TPR KDM4E 2072/4885LMNA 3563/4885CCR1 1369/4885
US-20080194590-A1 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors PFKP, PF4, P2RY4 KDM4E 2325/4885LMNA 2530/4885CCR1 2581/4885
US-20160372678-A1 CYCLIC AZINE COMPOUND HAVING ADAMANTYL GROUP, PRODUCTION METHOD, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING IT AS CONSTITUENT COMPONENT CHRM1, AFF1, AZI2 KDM4E 2202/4885LMNA 2153/4885CCR1 1586/4885
US-20080200475-A1 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors PF4, TBXA2R, P2RY4 KDM4E 2775/4885LMNA 3156/4885CCR1 2837/4885
US-20120248429-A1 TRIPHENYLENE BASED AROMATIC COMPOUNDS AND OLEDS UTILIZING THE SAME OCIAD1, TYR, TPR KDM4E 2072/4885LMNA 3563/4885CCR1 1369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.