Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 4/20 | 0.46 |
| ▸ | CCR5 | P51681 | 4/20 | 0.46 |
| ▸ | CCR8 | P51685 | 3/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11992064 | 0.81 | CCR1 (0.57) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL16125081 | 0.78 | CYP1A2 (0.43) | MEN1KMT2ACYP1A2CCR1CCR5 | |
| SCHEMBL9533951 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL29354893 | 0.77 | CCR1 (0.55) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL7509409 | 0.77 | CCR1 (0.58) | LMNAKDM4EKMT2ACYP1A2CCR1 | |
| SCHEMBL28304525 | 0.77 | CCR1 (0.55) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL8193 | 0.77 | CCR1 (0.55) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL1089189 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL29400608 | 0.76 | CCR1 (0.70) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL3193864 | 0.76 | CCR1 (0.70) | ALDH1A1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 730 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383856-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2024-11-21 | — | — | US | claimed |
| US-20240376055-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2024-11-14 | — | — | US | claimed |
| CN-118270777-A | Application of nucleoside modified graphene oxide in chiral compound recognition | 北京交通大学 | 2024-07-02 | — | — | CN | claimed |
| CN-110272417-B | 2-methyl-1, 8-naphthyridine compound and preparation method and application thereof | 五邑大学 | 2021-07-13 | — | — | CN | claimed |
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | claimed |
| CN-110272417-A | 2- methyl-1,8- naphthyridine type compound and the preparation method and application thereof | 五邑大学 | 2019-09-24 | — | — | CN | claimed |
| CN-106045996-B | A kind of 2- (2 '-hydroxy styrenes base) naphthyridines probe reagents and its preparation and application | 贵州大学 | 2018-06-19 | — | — | CN | claimed |
| CN-104974181-B | 1, 8-naphthyridine binuclear copper (I) complex, preparation method and application | 中国科学院理化技术研究所 | 2017-01-25 | — | — | CN | claimed |
| CN-106252686-A | A kind of can the hydrogen energy power generation system of hydrogen-preparing hydrogen-storing | 温州集智科技有限公司 | 2016-12-21 | — | — | CN | claimed |
| CN-106045996-A | 2-(2'-hydroxyl styryl) naphthyridine probe reagent and preparation and application thereof | 贵州大学 | 2016-10-26 | — | — | CN | claimed |
| EP-4159727-B1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC INC (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4665458-A1 | INHIBITING ALPHA V BETA8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| US-12459942-B2 | Inhibiting (α-v)(β-6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| US-12415796-B2 | Inhibitors of (αv)(β6) integrin | MORPHIC THERAPEUTIC, INC. (US) | 2025-09-16 | — | — | US | disclosed |
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |
| US-4273862-A | ANIONIC CYANINE DYE, HYDROQUINONE FRBRLOPRT | MITSUBISHI PAPER MILLS, LTD. (JP) | 1981-06-16 | — | — | US | disclosed |
| US-4259439-A | DIMETHINECYANINE DYE SENSITIZER | MITSUBISHI PAPER MILLS, LTD. (JP) | 1981-03-31 | — | — | US | disclosed |
| US-4175965-A | SILVER HALIDE EMULSION CONTAINING AN ELECTRON ACCEPTOR AND A SENSITIZING DYE | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-11-27 | — | — | US | disclosed |
| US-4147554-A | 5,6-DIHYDRO-PYRROLO(2,1-A)ISOQUINOLINES | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4134769-A | BETAINE AND ANIONIC TYPE CYANINE DYES | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459942-B2 | Inhibiting (α-v)(β-6) integrin | ITGB6, ITGA6, ITGAV | ALDH1A1 1629/4885LMNA 2251/4885KDM4E 3386/4885 |
| US-12415796-B2 | Inhibitors of (αv)(β6) integrin | ITGB6, ITGA6, ITGAV | ALDH1A1 2417/4885LMNA 2741/4885KDM4E 3739/4885 |
| US-20240383856-A1 | INHIBITORS OF TRANSGLUTAMINASES | TGM2, TGM3, TGM1 | ALDH1A1 1825/4885LMNA 2598/4885KDM4E 967/4885 |
| US-20240376055-A1 | INHIBITORS OF TRANSGLUTAMINASES | TGM2, TGM3, TGM1 | ALDH1A1 1825/4885LMNA 2598/4885KDM4E 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.