SCHEMBL25289337

SCHEMBL25289337

NNC(=O)[C@H](CC1CCCCC1)NC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 10/20 0.46
CTSS P25774 2/20 0.45
CTSK P43235 2/20 0.45
CTSL P07711 2/20 0.44
CTSB P07858 1/20 0.44
CHRNB2 P17787 5/20 0.43
CHRNB4 P30926 5/20 0.43
CHRNA3 P32297 5/20 0.43
CHRNA4 P43681 5/20 0.43
GRIN1 Q05586 2/20 0.43
GRIN2A Q12879 2/20 0.43
GRM1 Q13255 2/20 0.43
ALDH1A1 P00352 1/20 0.43
KMT2A Q03164 1/20 0.43
GRN P28799 1/20 0.43
SORT1 Q99523 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25242606 1.00 CPB2 (0.46) CPB2CTSSCTSKCTSLCTSB
SCHEMBL25247963 0.91 CTSS (0.41) CPB2CTSSCTSKCTSLCTSB
SCHEMBL25285773 0.91 CTSS (0.41) CPB2CTSSCTSKCTSLCTSB
SCHEMBL6477536 0.83 ALDH1A1 (0.43) CPB2CTSSCTSKCTSLCTSB
SCHEMBL6477529 0.83 ALDH1A1 (0.43) CPB2CTSSCTSKCTSLCTSB
SCHEMBL13735669 0.81 MMP1 (0.47) CPB2CTSSCTSKCTSLCTSB
SCHEMBL4971388 0.81 CTSS (0.52) CPB2CTSSCTSKCTSLCTSB
SCHEMBL13737104 0.80 CPB2 (0.55) CPB2CTSSCTSKCTSLCTSB
SCHEMBL12831363 0.80 CTSL (0.70) CTSSCTSKCTSLCTSBCHRNB2
SCHEMBL9595060 0.80 CPB2 (0.54) CPB2CTSSCTSKCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4204393-A1 AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS F. Hoffmann-La Roche AG (CH) 2023-07-05 EP disclosed