Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28783779 | 0.79 | HPGD (0.37) | HPGDALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL24136853 | 0.76 | OPRM1 (0.50) | HPGDALDH1A1KDM4ECHRM2CHRM1 | |
| SCHEMBL9690903 | 0.71 | CHRM2 (0.51) | ALDH1A1KDM4ELMNACHRM2NPC1 | |
| SCHEMBL26125381 | 0.71 | HPGD (0.74) | HPGDALDH1A1GLAHSD17B10HTT | |
| SCHEMBL13280179 | 0.71 | HPGD (0.74) | HPGDALDH1A1GLAHSD17B10HTT | |
| SCHEMBL18429032 | 0.70 | CHRM2 (0.50) | ALDH1A1KDM4ELMNACHRM2NPC1 | |
| SCHEMBL28614652 | 0.69 | ACHE (0.46) | HPGDALDH1A1HTTKDM4EPOLB | |
| SCHEMBL6630978 | 0.68 | SMN1; SMN2 (0.50) | HPGDALDH1A1HSD17B10HTTKDM4E | |
| SCHEMBL14646671 | 0.68 | FKBP1A (0.56) | ALDH1A1HSD17B10HTTSIGMAR1NPC1 | |
| SCHEMBL25756732 | 0.68 | FKBP1A (0.56) | ALDH1A1HSD17B10HTTSIGMAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |