Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25298309 | 0.93 | NR1D1 (0.40) | NR1D1MAPTCTPS1TP53HTT | |
| SCHEMBL25301553 | 0.92 | CHEK2 (0.41) | NR1D1MAPTCHEK2ALDH1A1MMP13 | |
| SCHEMBL25303036 | 0.91 | HPGD (0.35) | POLBSMN1; SMN2NR1D1MAPTHTT | |
| SCHEMBL25294461 | 0.91 | GPR119 (0.39) | NR1D1MAPTCTPS1TP53HTT | |
| SCHEMBL25251188 | 0.89 | MAPT (0.34) | LMNAPOLBSMN1; SMN2NR1D1NR1H2 | |
| SCHEMBL28561982 | 0.87 | RBP4 (0.41) | LMNAPOLBSMN1; SMN2NR1D1NR1H2 | |
| SCHEMBL28562235 | 0.85 | CHEK2 (0.39) | LMNAPOLBSMN1; SMN2NR1D1NR1H2 | |
| SCHEMBL25295921 | 0.85 | NR1D1 (0.39) | NR1D1MAPTGPR119ALDH1A1MMP13 | |
| SCHEMBL25298978 | 0.84 | ALDH1A1 (0.38) | LMNAPOLBMAPTHTTGPR119 | |
| SCHEMBL25299048 | 0.84 | GPR119 (0.37) | POLBNR1D1MAPTCTPS1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463450-A1 | FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS | Bisichem Co., Ltd. (KR) | 2024-11-20 | — | — | EP | disclosed |
| CN-118510770-A | Fused heteroaryl hydroxamic acids as STING agonists | 比西切姆有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023136589-A1 | FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS | BISICHEM CO., LTD. (KR) | 2023-07-20 | — | — | WO | disclosed |
| US-20230219931-A1 | FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS | BISICHEM CO., LTD. (KR) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219931-A1 | FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS | STING1, IRF3, IFNAR1 | LMNA 2977/4885POLB 183/4885SMN1; SMN2 3686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.