Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437896 | 0.78 | ERBB2 (0.32) | PLCG1ERBB2MAPTPRKCIALDH1A1 | |
| SCHEMBL6170131 | 0.78 | NOS3 (0.46) | PLCG1ERBB2MAPTNOS3NOS2 | |
| SCHEMBL17570530 | 0.77 | TSHR (0.37) | PIM1PLCG1ERBB2MAPTNOS3 | |
| SCHEMBL17416894 | 0.75 | MEN1 (0.39) | PLCG1ERBB2MAPTPRKCIALDH1A1 | |
| SCHEMBL30527748 | 0.75 | MEN1 (0.39) | PLCG1ERBB2MAPTPRKCIALDH1A1 | |
| SCHEMBL14842294 | 0.75 | TDO2 (0.33) | ERBB2PRKCI | |
| SCHEMBL3360364 | 0.75 | KDM4E (0.36) | ERBB2PRKCIALDH1A1POLBLRRK2 | |
| SCHEMBL4385912 | 0.75 | PLCG1 (0.35) | PLCG1ERBB2MAPTNOS3NOS2 | |
| SCHEMBL1841305 | 0.75 | CCR1 (0.35) | NTRK1PIM1ACVR1PLCG1ERBB2 | |
| SCHEMBL2671146 | 0.75 | ALDH1A1 (0.40) | NTRK1PIM1ACVR1PLCG1ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974872-B | Azacyclic derivatives, pharmaceutical compositions thereof and uses thereof | 南方科技大学 | 2025-05-02 | — | — | CN | disclosed |
| WO-2023134713-A1 | FUSED AZAHETEROCYCLIC DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 南方科技大学 | 2023-07-20 | — | — | WO | disclosed |
| CN-115974872-A | Aza-and-ring derivatives, pharmaceutical compositions thereof and uses thereof | 南方科技大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-110139862-A | It can be used as the bicyclic heterocycles derivative of ROMK channel inhibitor being substituted | 百时美施贵宝公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-107001342-A | Novel compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-104710420-B | Azabicyclic formula compound or its salt, containing its medicine, compositions and application | 大鹏药品工业株式会社 | 2016-07-27 | — | — | CN | disclosed |
| CN-103492385-B | Be used for the treatment of the noval chemical compound of degenerative disease and inflammatory disease | GALAPAGOS N.V. (BE) | 2016-05-11 | — | — | CN | disclosed |
| CN-103492386-B | Novel compounds useful for the treatment of degenerative and inflammatory diseases | GALAPAGOS N.V. (BE) | 2016-03-09 | — | — | CN | disclosed |
| CN-103596953-A | Pyridonaphthyridine PI3K/mTOR dual inhibitors and preparation and use thereof | KBP BIOSCIENCES CO LTD | 2014-02-19 | — | — | CN | disclosed |
| CN-103492386-A | Novel compounds useful for the treatment of degenerative and inflammatory diseases | GALAPAGOS NV | 2014-01-01 | — | — | CN | disclosed |
| CN-103492385-A | Novel compound useful for the treatment of degenerative and inflammatory diseases | GALAPAGOS NV | 2014-01-01 | — | — | CN | disclosed |
| CN-1433413-A | Oxazolidinone derivatives and process for their preparation | DONG A PHARM CO LTD (KR) | 2003-07-30 | — | — | CN | disclosed |