Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.35 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.35 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | FLT1 | P17948 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | GSK3A | P49840 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671909 | 0.80 | TSHR (0.38) | TSHRNISCHROCK2ROCK1CDC42BPA | |
| SCHEMBL6170131 | 0.80 | NOS3 (0.46) | TSHRLRRK2PLCG1ERBB2MAPT | |
| SCHEMBL4385912 | 0.77 | PLCG1 (0.35) | LRRK2ARPLCG1ERBB2MAPT | |
| SCHEMBL22647247 | 0.77 | NOS2 (0.54) | TSHRNISCHROCK2ROCK1CDC42BPA | |
| SCHEMBL1119092 | 0.77 | FFAR1 (0.42) | TSHRNISCHROCK2ROCK1CDC42BPA | |
| SCHEMBL25299754 | 0.77 | NTRK1 (0.33) | LRRK2PLCG1ERBB2MAPTNOS3 | |
| SCHEMBL15758260 | 0.77 | FFAR1 (0.42) | TSHRNISCHROCK2ROCK1CDC42BPA | |
| SCHEMBL11285134 | 0.77 | AR (0.36) | TSHRNISCHROCK2ROCK1CDC42BPA | |
| SCHEMBL2136972 | 0.77 | NISCH (0.36) | TSHRNISCHROCK2ROCK1CDC42BPA | |
| SCHEMBL2671146 | 0.77 | ALDH1A1 (0.40) | LRRK2PLCG1ERBB2MAPTPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375785-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-08-05 | — | — | EP | disclosed |
| US-20200131150-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2020-04-30 | — | — | US | disclosed |
| US-10193079-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-01-29 | — | — | US | disclosed |
| EP-2976329-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-06-27 | — | — | EP | disclosed |
| US-20160072076-A1 | MATERIALS FOR ELECTRONIC DEVICES | UDC IRELAND LIMITED (IE) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160072076-A1 | MATERIALS FOR ELECTRONIC DEVICES | AOC3, AOC2, AOC1 | TSHR 3000/4885NISCH 11/4885ROCK2 4375/4885 |
| US-20200131150-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CCNT1, CCNA1, CCNE2 | TSHR 3582/4885NISCH 2703/4885ROCK2 3111/4885 |
| US-10193079-B2 | Materials for electronic devices | AOC3, AOC2, AOC1 | TSHR 3000/4885NISCH 11/4885ROCK2 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.