Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | MLYCD | O95822 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255266 | 0.82 | ALOX5 (0.50) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6359725 | 0.81 | TDP1 (0.58) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14282039 | 0.80 | TDP1 (0.46) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7279484 | 0.78 | FAAH (0.49) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6967760 | 0.78 | RCE1 (0.49) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6956260 | 0.78 | RCE1 (0.49) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6961364 | 0.78 | MAOA (0.54) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL13181406 | 0.77 | MLYCD (0.64) | KMT2ACES1FAAHMLYCD | |
| SCHEMBL7374440 | 0.77 | ALOX5 (0.58) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL11241052 | 0.77 | TDP1 (0.57) | TDP1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425754-A | Aromatic heterobicyclic compounds and antiviral uses thereof | 苏州爱科百发生物医药技术有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023125845-A1 | HETEROAROMATIC BICYCLIC COMPOUND AND ANTIVIRAL APPLICATION THEREOF | 苏州爱科百发生物医药技术有限公司 | 2023-07-06 | — | — | WO | disclosed |