Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | CES1 | P23141 | 3/20 | 0.49 |
| ▸ | MLYCD | O95822 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10540038 | 0.83 | MTNR1A (0.44) | MEN1KMT2A | |
| SCHEMBL25301481 | 0.78 | TDP1 (0.50) | FAAHCES1MLYCDHDAC1NPC1 | |
| SCHEMBL6961364 | 0.75 | MAOA (0.54) | FAAHCES1MLYCDNPC1RAB9A | |
| SCHEMBL14282039 | 0.74 | TDP1 (0.46) | FAAHCES1MLYCDNPC1RAB9A | |
| SCHEMBL6463897 | 0.74 | FAAH (0.54) | FAAHCES1MLYCDALOX5SIGMAR1 | |
| SCHEMBL901839 | 0.72 | REN (0.50) | HDAC1MEN1KMT2AMAPTHDAC8 | |
| SCHEMBL6967760 | 0.72 | RCE1 (0.49) | FAAHCES1MLYCDHDAC1NPC1 | |
| SCHEMBL6956260 | 0.72 | RCE1 (0.49) | FAAHCES1MLYCDHDAC1NPC1 | |
| SCHEMBL7985986 | 0.72 | MLYCD (0.54) | FAAHCES1MLYCDALOX5SIGMAR1 | |
| SCHEMBL25047881 | 0.71 | L3MBTL1 (0.47) | HDAC1NPC1RAB9ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375668-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1990-06-27 | — | — | EP | disclosed |
| US-4868306-A | Compounds | FISONS PLC (GB) | 1989-09-19 | — | — | US | disclosed |
| US-4791216-A | Para ethyl amino phenol pharmaceutical compounds | FISONS PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| US-4657929-A | Compounds | FISONS PLC (GB) | 1987-04-14 | — | — | US | disclosed |
| EP-0142283-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1985-05-22 | — | — | EP | disclosed |