SCHEMBL25306451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25850497	1.00	JAK2 (0.36)	JAK2JAK1GBA1IDH1CTSK
	SCHEMBL24154957	1.00	JAK2 (0.36)	JAK2JAK1GBA1IDH1CTSK
	SCHEMBL30283045	1.00	JAK2 (0.36)	JAK2JAK1GBA1IDH1CTSK
	SCHEMBL25306447	1.00	JAK2 (0.36)	JAK2JAK1GBA1IDH1CTSK
	SCHEMBL24154923	0.86	JAK2 (0.38)	JAK2JAK1GBA1IDH1CTSK
	SCHEMBL24155296	0.86	JAK2 (0.38)	JAK2JAK1GBA1IDH1CTSK
	SCHEMBL25307503	0.86	JAK2 (0.38)	JAK2JAK1GBA1IDH1CTSK
	SCHEMBL30283042	0.82	ALDH1A1 (0.39)	JAK2JAK1GBA1IDH1CTSK
	SCHEMBL24154769	0.78	CTSK (0.42)	CTSKALDH1A1MBOAT4PDE1APDE1B
	SCHEMBL30319984	0.78	CTSK (0.42)	CTSKALDH1A1MBOAT4PDE1APDE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.