Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 18/20 | 0.62 |
| ▸ | PARP2 | Q9UGN5 | 8/20 | 0.62 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310803 | 0.89 | PARP1 (0.61) | PARP1PARP2TNKSTIPARP | |
| SCHEMBL25263299 | 0.86 | TNKS (0.53) | PARP1PARP2TNKSTIPARP | |
| SCHEMBL25310671 | 0.84 | CHRM1 (0.49) | PARP1PARP2TNKSTIPARP | |
| SCHEMBL30510764 | 0.84 | CHRM1 (0.49) | PARP1PARP2TNKSTIPARP | |
| SCHEMBL25308789 | 0.84 | TNKS (0.51) | PARP1TNKSTIPARP | |
| SCHEMBL25308938 | 0.82 | TNKS (0.57) | PARP1PARP2TNKS | |
| SCHEMBL30510770 | 0.82 | TNKS (0.51) | PARP1PARP2TNKS | |
| SCHEMBL30510772 | 0.82 | TNKS (0.51) | PARP1PARP2TNKS | |
| SCHEMBL25309465 | 0.80 | TNKS (0.49) | PARP1TNKS | |
| SCHEMBL25310056 | 0.80 | TNKS (0.49) | PARP1PARP2TNKSTIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139536-A1 | (4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | WO | claimed |
| WO-2023139536-A1 | (4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | WO | disclosed |