Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.42 |
| ▸ | SCD | O00767 | 7/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253733 | 0.80 | SYK (0.45) | SYKSCDCXCR3 | |
| SCHEMBL253233 | 0.79 | SYK (0.40) | SYKGPR52 | |
| SCHEMBL13186819 | 0.79 | SYK (0.43) | SYKSCDCXCR3PDE4D | |
| SCHEMBL255347 | 0.78 | SYK (0.38) | SYKROCK2IRAK4KCNH2 | |
| SCHEMBL253124 | 0.76 | STAMBP (0.44) | SYKSCDROCK2PDE4D | |
| SCHEMBL248207 | 0.73 | CSF1R (0.43) | GPR52NTRK1KCNH2NTRK3 | |
| SCHEMBL253705 | 0.73 | AURKA (0.47) | GPR52 | |
| SCHEMBL252286 | 0.73 | PARP1 (0.41) | — | |
| SCHEMBL250721 | 0.70 | SYK (0.65) | SYKSCDPDE4D | |
| SCHEMBL619849 | 0.68 | SYK (0.59) | SYKSCDPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | claimed |