Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAMBP | O95630 | 6/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 5/20 | 0.44 |
| ▸ | NAMPT | P43490 | 5/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 2/20 | 0.42 |
| ▸ | COPS5 | Q92905 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253733 | 0.85 | SYK (0.45) | SYKSCDEPHX2 | |
| SCHEMBL253234 | 0.80 | PSMD14 (0.50) | STAMBPPSMD14COPS5MAPK1 | |
| SCHEMBL255348 | 0.78 | NAMPT (0.52) | STAMBPPSMD14NAMPTCOPS5MAPK1 | |
| SCHEMBL619849 | 0.77 | SYK (0.59) | SYKSCDEPHX2PDE4D | |
| SCHEMBL253123 | 0.76 | SYK (0.42) | SYKSCDPDE4DROCK2 | |
| SCHEMBL248208 | 0.74 | TRPV1 (0.47) | STAMBPPSMD14EPHX2 | |
| SCHEMBL253706 | 0.74 | MLYCD (0.58) | STAMBPPSMD14NAMPTCOPS5ROCK2 | |
| SCHEMBL252287 | 0.73 | STAMBP (0.51) | STAMBPPSMD14NAMPTCOPS5 | |
| SCHEMBL10232978 | 0.73 | SYK (0.54) | NAMPTSYKEPHX2PDE4D | |
| SCHEMBL13186819 | 0.73 | SYK (0.43) | SYKSCDPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | claimed |