SCHEMBL25314971

SCHEMBL25314971

COC(=O)c1cc(C(=O)OC)cc(N2C(=O)c3ccccc3C2=O)c1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.56
ALDH1A1 P00352 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA9 Q16790 2/20 0.51
CA4 P22748 1/20 0.51
SCN2A Q99250 2/20 0.50
CA12 O43570 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
POLB P06746 3/20 0.49
TDP1 Q9NUW8 1/20 0.49
PLA2G1B P04054 1/20 0.49
ATG4B Q9Y4P1 1/20 0.49
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27570670 0.85 PLA2G1B (0.65) ALDH1A1CA1CA2CA9CA4
SCHEMBL19168010 0.83 CA1 (0.46) HPGDALDH1A1L3MBTL1CA1CA2
SCHEMBL30887365 0.83 CA1 (0.46) HPGDALDH1A1L3MBTL1CA1CA2
SCHEMBL25314162 0.83 CA1 (0.46) HPGDALDH1A1L3MBTL1CA1CA2
SCHEMBL7911548 0.82 ALDH1A1 (0.61) HPGDALDH1A1L3MBTL1MAPK1HSD17B10
SCHEMBL19176480 0.82 CA1 (0.50) HPGDALDH1A1L3MBTL1CA1CA2
SCHEMBL7904992 0.81 PLA2G1B (0.60) HPGDALDH1A1L3MBTL1CA1CA2
SCHEMBL8586537 0.81 CA9 (0.55) HPGDALDH1A1L3MBTL1CA1CA2
SCHEMBL13132607 0.81 CA1 (0.49) HPGDALDH1A1L3MBTL1CA1CA2
SCHEMBL19168009 0.80 ALDH1A1 (0.43) HPGDALDH1A1L3MBTL1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof SICHUAN UNIVERSITY (CN) 2026-02-24 US disclosed
US-20230235116-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT ANTI-DRIPPING COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SICHUAN UNIVERSITY (CN) 2023-07-27 US disclosed
EP-4169967-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT DROPLET-RESISTANT COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Sichuan University (CN) 2023-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof COL1A1, F11, COL2A1 HPGD 3971/4885ALDH1A1 269/4885L3MBTL1 350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.