Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530843 | 0.88 | CA1 (0.40) | CA1MGLLADRA2AADRA1AMAPT | |
| SCHEMBL2531968 | 0.88 | MGLL (0.46) | CA1MGLLADRA2AADRA1AMAPT | |
| SCHEMBL4292777 | 0.86 | CYP19A1 (0.49) | CA1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL2528042 | 0.86 | CA1 (0.39) | CA1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL433535 | 0.86 | DGKA (0.47) | MGLLMAPTDGKATDP1TSHR | |
| SCHEMBL821822 | 0.85 | ADRA2A (0.43) | MGLLADRA2AADRA1AMAPTBLM | |
| SCHEMBL14308492 | 0.84 | CA1 (0.44) | CA1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL25886908 | 0.84 | CA1 (0.44) | CA1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL2533187 | 0.84 | NAAA (0.41) | CA1DGKAACHECNR1CNR2 | |
| SCHEMBL2529017 | 0.84 | NAAA (0.41) | CA1DGKAACHECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| CN-103060030-B | Diesel additive composition containing alkyl ethylene glycol acetamide and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | disclosed |
| CN-103060029-B | Diesel additive composition containing alkyl ethylene glycol acetic acid polyol ester and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-03-18 | — | — | CN | disclosed |
| CN-102453561-B | Diesel oil additive and application thereof to low-sulfur diesel oil | CHINA PETROLEUM & CHEMICAL | 2014-05-28 | — | — | CN | disclosed |
| CN-102453562-B | Organic amide low-sulfur diesel oil lubrication additive and application thereof | CHINA PETROLEUM & CHEMICAL | 2014-04-30 | — | — | CN | disclosed |
| US-8637557-B2 | Aminothiazole derivative | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2014-01-28 | — | — | US | disclosed |
| CN-103060029-A | Diesel additive composition containing alkyl ethylene glycol acetic acid polyol ester and application thereof | CHINA PETROLEUM & CHEMICAL | 2013-04-24 | — | — | CN | disclosed |
| CN-103060030-A | Diesel additive composition containing alkyl ethylene glycol acetamide and application thereof | CHINA PETROLEUM & CHEMICAL | 2013-04-24 | — | — | CN | disclosed |
| US-20120220767-A1 | AMINOTHIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
| US-5830936-A | THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220767-A1 | AMINOTHIAZOLE DERIVATIVE | AKT3, AKT2, JAK1 | CA1 4541/4885MGLL 462/4885ADRA2A 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.