Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25323166 | 0.82 | NOS1 (0.49) | NOS3NOS1NOS2KDM4EMAPT | |
| SCHEMBL25323163 | 0.82 | NOS1 (0.49) | NOS3NOS1NOS2KDM4EMAPT | |
| SCHEMBL25920105 | 0.82 | NOS1 (0.49) | NOS3NOS1NOS2KDM4EMAPT | |
| SCHEMBL25321059 | 0.81 | MEN1 (0.41) | GRIN2BKDM4EMEN1KMT2A | |
| SCHEMBL30551331 | 0.81 | MEN1 (0.41) | GRIN2BKDM4EMEN1KMT2A | |
| SCHEMBL25920106 | 0.81 | MEN1 (0.41) | GRIN2BKDM4EMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL25325870 | 0.75 | NOS3 (0.41) | NOS3NOS1NOS2CHRNB4CHRNA3 | |
| SCHEMBL14065400 | 0.68 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL6924404 | 0.68 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL4865057 | 0.68 | MEN1 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |