SCHEMBL2532457

SCHEMBL2532457

CCCCCCCCC/C=C/C=C/C=C/C=C/C=C(/C(=O)O)[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.51
PPARG P37231 8/20 0.45
PPARA Q07869 3/20 0.45
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
FAAH O00519 4/20 0.44
KDM4E B2RXH2 1/20 0.44
TRPA1 O75762 1/20 0.43
FBP1 P09467 1/20 0.43
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2532462 1.00 FASN (0.51) FASNPPARGPPARAALDH1A1TSHR
SCHEMBL2533250 1.00 FASN (0.51) FASNPPARGPPARAALDH1A1TSHR
SCHEMBL16038842 1.00 FASN (0.51) FASNPPARGPPARAALDH1A1TSHR
SCHEMBL16038846 1.00 FASN (0.51) FASNPPARGPPARAALDH1A1TSHR
SCHEMBL2533246 1.00 FASN (0.51) FASNPPARGPPARAALDH1A1TSHR
SCHEMBL6369891 0.78 PPARG (0.58) PPARGPPARAFAAHTRPA1FBP1
SCHEMBL1055870 0.78 FASN (0.61) FASNPPARGPPARAALDH1A1TSHR
SCHEMBL2732862 0.78 FASN (0.61) FASNPPARGPPARAALDH1A1TSHR
SCHEMBL1039992 0.78 FASN (0.61) FASNPPARGPPARAALDH1A1TSHR
SCHEMBL21925330 0.78 PPARG (0.58) PPARGPPARAFAAHTRPA1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064491-A1 METHODS FOR FAT REDUCTION NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2025-03-27 WO claimed
US-9308189-B2 Nitro fatty acids—neuroprotection and/or inhibition of cognitive decline NITROMEGA CORP. (US) 2016-04-12 US claimed
CN-102843922-B The neuroprotective of Xiao base Zhi Fang Suan – cognitive decline and/or suppression NITROMEGA CORP. (US) 2015-12-16 CN claimed
CN-104288138-A Nutraceuticals containing nitro fatty acids NITROMEGA CORP 2015-01-21 CN claimed
US-20140271844-A1 COMPOSITIONS CONTAINING NITRO FATTY ACIDS COMPLEXA, INC. 2014-09-18 US claimed
EP-2726086-A2 COMPOSITIONS CONTAINING NITRO FATTY ACIDS Nitromega Corp. (US) 2014-05-07 EP claimed
US-20140017219-A1 NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE NITROMEGA CORP. (US) 2014-01-16 US claimed
US-8563609-B2 Nitro fatty acids - neuroprotection and/or inhibition of cognitive decline NITROMEGA CORP. (US) 2013-10-22 US claimed
WO-2013003689-A2 COMPOSITIONS CONTAINING NITRO FATTY ACIDS NITROMEGA CORP. (US) 2013-01-03 WO claimed
CN-102843922-A Nitro fatty acids - neuroprotection and/or inhibition of cognitive decline NITROMEGA CORP 2012-12-26 CN claimed
CN-102307464-A Nutrition product containing nitro fatty acid NITROMEGA CORP 2012-01-04 CN claimed
US-20110280852-A1 NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE NITROMEGA CORP. (US) 2011-11-17 US claimed
US-20100166918-A1 NUTRACEUTICALS CONTAINING NITRO FATTY ACIDS COMPLEXA, INC. 2010-07-01 US claimed
US-20160256508-A1 COMPOSITIONS CONTAINING NITRO FATTY ACIDS COMPLEXA, INC. 2016-09-08 US disclosed
US-9308189-B2 Nitro fatty acids—neuroprotection and/or inhibition of cognitive decline NITROMEGA CORP. (US) 2016-04-12 US disclosed
CN-102843922-B The neuroprotective of Xiao base Zhi Fang Suan – cognitive decline and/or suppression NITROMEGA CORP. (US) 2015-12-16 CN disclosed
EP-2384114-A1 NUTRACEUTICALS CONTAINING NITRO FATTY ACIDS Nitromega Corp. (US) 2011-11-09 EP disclosed
US-20110256247-A1 TOPICAL COMPOSITIONS CONTAINING NITRO FATTY ACIDS NITROMEGA CORP. (US) 2011-10-20 US disclosed
WO-2010078504-A1 NUTRACEUTICALS CONTAINING NITRO FATTY ACIDS NITROMEGA CORP. (US) 2010-07-08 WO disclosed
US-20100166918-A1 NUTRACEUTICALS CONTAINING NITRO FATTY ACIDS COMPLEXA, INC. 2010-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140271844-A1 COMPOSITIONS CONTAINING NITRO FATTY ACIDS ALOX5, FASN, ALOX12 FASN 2/4885PPARG 26/4885PPARA 58/4885
US-20110256247-A1 TOPICAL COMPOSITIONS CONTAINING NITRO FATTY ACIDS ALOX5, FASN, FPR1 FASN 2/4885PPARG 25/4885PPARA 33/4885
US-20140017219-A1 NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE NLN, SMN1; SMN2, ELOVL1 FASN 22/4885PPARG 51/4885PPARA 73/4885
US-20110280852-A1 NITRO FATTY ACIDS - NEUROPROTECTION AND/OR INHIBITION OF COGNITIVE DECLINE NLN, SMN1; SMN2, CASP10 FASN 40/4885PPARG 88/4885PPARA 142/4885
US-20160256508-A1 COMPOSITIONS CONTAINING NITRO FATTY ACIDS ALOX5, FASN, ALOX12 FASN 2/4885PPARG 26/4885PPARA 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.