⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322943 | 0.91 | CHRNB2 (0.30) | — | |
| SCHEMBL30551316 | 0.91 | CHRNB2 (0.30) | — | |
| SCHEMBL16913805 | 0.80 | PIK3C3 (0.35) | — | |
| SCHEMBL25324652 | 0.75 | PIK3C3 (0.35) | — | |
| SCHEMBL16913982 | 0.70 | PIK3C3 (0.38) | — | |
| SCHEMBL30867441 | 0.66 | POLB (0.43) | — | |
| SCHEMBL31459178 | 0.64 | ALDH1A1 (0.42) | — | |
| SCHEMBL26685022 | 0.64 | NNMT (0.36) | — | |
| SCHEMBL3450931 | 0.64 | ALDH1A1 (0.42) | — | |
| SCHEMBL4014634 | 0.64 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |