Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326718 | 0.80 | GPR119 (0.48) | USP30 | |
| SCHEMBL23091827 | 0.79 | HDAC1 (0.46) | ACMSDHDAC1NPC1RAB9AATM | |
| SCHEMBL15173662 | 0.79 | HDAC1 (0.44) | USP30ACMSDHDAC1HDAC2NPC1 | |
| SCHEMBL25249861 | 0.79 | KDM1A (0.45) | USP30ACMSDHDAC1HDAC2NPC1 | |
| SCHEMBL25325512 | 0.78 | SLC9A1 (0.43) | ACMSDKMOFASN | |
| SCHEMBL21381933 | 0.78 | KDM1A (0.49) | USP30FASN | |
| SCHEMBL13738768 | 0.75 | SCD5 (0.50) | KMONPC1RAB9AATM | |
| SCHEMBL8328994 | 0.74 | OPRL1 (0.46) | ACMSDKMOHDAC2 | |
| SCHEMBL21381616 | 0.73 | PTGDR2 (0.43) | PTGDR2 | |
| SCHEMBL23212022 | 0.73 | EPHX2 (0.46) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |