Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.43 |
| ▸ | FASN | P49327 | 3/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 3/20 | 0.37 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25324931 | 0.84 | PDE4B (0.45) | — | |
| SCHEMBL25255668 | 0.81 | SLC6A9 (0.36) | SLC9A1TYK2QDPRSLC6A9POLB | |
| SCHEMBL30553403 | 0.78 | TYK2 (0.38) | SLC9A1DRD2DRD3TYK2 | |
| SCHEMBL25326686 | 0.78 | USP30 (0.41) | FASNKMOACMSD | |
| SCHEMBL25943823 | 0.75 | CYP2D6 (0.40) | SLC9A1KMODRD2DRD3TYK2 | |
| SCHEMBL23091827 | 0.75 | HDAC1 (0.46) | ACMSDALDH1A1POLBKMT2A | |
| SCHEMBL25260686 | 0.72 | FPR1 (0.39) | FASNKMOALDH1A1POLB | |
| SCHEMBL31401408 | 0.71 | SLC9A1 (0.53) | SLC9A1KMOKMT2A | |
| SCHEMBL13544340 | 0.71 | ACMSD (0.56) | KMOTYK2ACMSDMEN1ALDH1A1 | |
| SCHEMBL25325726 | 0.70 | LMNA (0.36) | SLC9A1DRD2DRD3TYK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |