Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 10/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328725 | 0.91 | HMGCR (0.43) | NR1H4LTB4RLTB4R2HMGCR | |
| SCHEMBL25328003 | 0.86 | ESR1 (0.49) | LTB4RLTB4R2ESR1SMPD1PGAM1 | |
| SCHEMBL25331008 | 0.86 | ESR1 (0.49) | NR1H4HMGCRESR1ESR2SMPD1 | |
| SCHEMBL25328958 | 0.82 | ALDH1A1 (0.44) | NR1H4LTB4RLTB4R2HMGCR | |
| SCHEMBL14154474 | 0.79 | TAAR1 (0.47) | HMGCRSMPD1 | |
| SCHEMBL25330210 | 0.76 | ALOX15 (0.43) | LTB4RLTB4R2HMGCR | |
| SCHEMBL28974846 | 0.76 | LMNA (0.41) | HMGCRESR1 | |
| SCHEMBL11024575 | 0.76 | HMGCR (0.58) | LTB4RLTB4R2HMGCRESR1SMPD1 | |
| SCHEMBL25329688 | 0.76 | ESR1 (0.40) | LTB4RESR1 | |
| SCHEMBL23070366 | 0.76 | PSEN1 (0.46) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583813-B2 | Polymerization inhibitors | BASF SE (DE) | 2026-03-24 | — | — | US | disclosed |
| US-20230242472-A1 | POLYMERIZATION INHIBITORS | BASF SE (DE) | 2023-08-03 | — | — | US | disclosed |
| CN-115697954-A | Polymerization inhibitor | 巴斯夫欧洲公司 | 2023-02-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242472-A1 | POLYMERIZATION INHIBITORS | RCE1, CABLES1, DPYD | NR1H4 4465/4885LTB4R 2433/4885LTB4R2 2600/4885 |
| US-12583813-B2 | Polymerization inhibitors | PTGS1, PTGER1, POT1 | NR1H4 4243/4885LTB4R 189/4885LTB4R2 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.