SCHEMBL25329288

SCHEMBL25329288

CCc1cc(O)c(C)c(C)c1OC(C)C

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 5/20 0.43
ALOX15 P16050 4/20 0.43
ALDH1A1 P00352 3/20 0.32
TSHR P16473 1/20 0.32
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
MAPT P10636 3/20 0.32
CYP3A4 P08684 1/20 0.31
ACHE P22303 1/20 0.31
MEN1 O00255 2/20 0.31
POLB P06746 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ICAM1 P05362 1/20 0.31
SELE P16581 1/20 0.31
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25327676 0.86 ALOX15 (0.41) ALOX12ALOX15ALDH1A1TSHRIDO1
SCHEMBL25329293 0.86 ALOX15 (0.41) ALOX12ALOX15ALDH1A1TSHRIDO1
SCHEMBL25327492 0.79 CYP3A4 (0.43) ALOX12ALOX15ALDH1A1CYP3A4
SCHEMBL30356405 0.79 ALOX15 (0.41) ALOX12ALOX15ALDH1A1MAPTGAA
SCHEMBL25330005 0.78 ALOX15 (0.37) ALOX12ALOX15ALDH1A1TSHRMAPT
SCHEMBL25329784 0.77 ACHE (0.36) ALOX12ALOX15ALDH1A1MAPTCYP3A4
SCHEMBL25328537 0.75 ALOX15 (0.35) ALOX12ALOX15CYP3A4ACHE
SCHEMBL25329439 0.75 ALDH1A1 (0.37) ALOX12ALOX15ALDH1A1MAPTMEN1
SCHEMBL25330034 0.74 THRA (0.40) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL25328780 0.74 SCN5A (0.32) ALOX12ALOX15ALDH1A1MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583813-B2 Polymerization inhibitors BASF SE (DE) 2026-03-24 US disclosed
US-20230242472-A1 POLYMERIZATION INHIBITORS BASF SE (DE) 2023-08-03 US disclosed
CN-115697954-A Polymerization inhibitor 巴斯夫欧洲公司 2023-02-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242472-A1 POLYMERIZATION INHIBITORS RCE1, CABLES1, DPYD ALOX12 1986/4885ALOX15 2186/4885ALDH1A1 1314/4885
US-12583813-B2 Polymerization inhibitors PTGS1, PTGER1, POT1 ALOX12 211/4885ALOX15 615/4885ALDH1A1 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.