Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL930845 | 1.00 | — | — | |
| Water SCHEMBL214101 | 1.00 | — | — | |
| Water SCHEMBL8207658 | 1.00 | — | — | |
| Water SCHEMBL9155131 | 1.00 | — | — | |
| Water SCHEMBL18315298 | 1.00 | — | — | |
| Water SCHEMBL113581 | 1.00 | — | — | |
| Water SCHEMBL27535961 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL15254215 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL93147 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL27952085 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240384951-A1 | HEAT EXCHANGER HAVING HYDROPHOBIC LAYER, COMPOSITE MATERIAL FOR HEAT EXCHANGER AND MANUFACTURING METHOD OF HEAT EXCHANGER | ZHEJIANG SANHUA INTELLIGENT CONTROLS CO., LTD. (CN) | 2024-11-21 | — | — | US | disclosed |
| US-20240384950-A1 | HEAT EXCHANGER, COMPOSITE MATERIAL FOR HEAT EXCHANGER, AND MANUFACTURING METHOD FOR HEAT EXCHANGER | ZHEJIANG SANHUA INTELLIGENT CONTROLS CO., LTD. (CN) | 2024-11-21 | — | — | US | disclosed |
| CN-115325851-B | Heat exchanger and method for manufacturing the same | 杭州三花研究院有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2024002119-A1 | HEAT EXCHANGER AND MANUFACTURING METHOD THEREFOR | 杭州三花研究院有限公司 | 2024-01-04 | — | — | WO | disclosed |
| US-20230358488-A1 | HEAT EXCHANGER, MANUFACTURING METHOD THEREOF AND THERMAL MANAGEMENT SYSTEM | Hangzhou Sanhua Research Institute Co., Ltd. (CN) | 2023-11-09 | — | — | US | disclosed |
| US-11807539-B2 | Heat exchanger and manufacturing method thereof | Hangzhou Sanhua Research Institute Co., Ltd. (CN) | 2023-11-07 | — | — | US | disclosed |
| CN-116790188-A | Liquid reservoir and method of manufacturing the same | 浙江三花智能控制股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-114754620-B | Heat exchanger and preparation method thereof | 杭州三花研究院有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116558326-A | Heat exchanger and composite material for heat exchanger | 浙江三花智能控制股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-116558327-A | Heat exchanger and composite material for heat exchanger | 浙江三花智能控制股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| WO-2023143324-A1 | HEAT EXCHANGER, COMPOSITE MATERIAL USED FOR HEAT EXCHANGER, AND SURFACE TREATMENT METHOD FOR HEAT EXCHANGER | 浙江三花智能控制股份有限公司 | 2023-08-03 | — | — | WO | disclosed |
| WO-2023143305-A1 | HEAT EXCHANGER, COMPOSITE MATERIAL FOR HEAT EXCHANGER, AND HEAT EXCHANGER SURFACE TREATMENT METHOD | 浙江三花智能控制股份有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-116067202-A | Heat exchanger and heat exchanger treatment method | 杭州三花研究院有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20230138311-A1 | HEAT EXCHANGER AND METHOD THEREOF PROCESSING THE SAME | Hangzhou Sanhua Research Institute Co., Ltd. (CN) | 2023-05-04 | — | — | US | disclosed |
| CN-115325851-A | Heat exchanger and method for manufacturing same | 杭州三花研究院有限公司 | 2022-11-11 | — | — | CN | disclosed |
| US-20220250921-A1 | HEAT EXCHANGER AND MANUFACTURING METHOD THEREOF | Hangzhou Sanhua Research Institute Co., Ltd. (CN) | 2022-08-11 | — | — | US | disclosed |
| CN-114754620-A | Heat exchanger and preparation method thereof | 杭州三花研究院有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114739206-A | Heat exchanger and preparation method thereof | 杭州三花研究院有限公司 | 2022-07-12 | — | — | CN | disclosed |