Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114539 | 0.89 | RAB9A (0.53) | MKNK2CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL25337392 | 0.79 | MAPT (0.51) | CDK2RAB9APOLBMAPTNPC1 | |
| SCHEMBL27789789 | 0.78 | RAB9A (0.46) | CDC7RAB9APOLBNPC1SMN1; SMN2 | |
| SCHEMBL956156 | 0.76 | CDC7 (0.43) | MKNK2CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL6597674 | 0.76 | HPGDS (0.53) | PIM1CLK4SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8691392 | 0.76 | CA2 (0.54) | CDK2 | |
| SCHEMBL28562593 | 0.76 | SMN1; SMN2 (0.54) | KDRRAB9APOLBMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL1194018 | 0.75 | HPGDS (0.52) | PIM1CLK4SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL16746748 | 0.74 | MPO (0.46) | MKNK2CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL3842147 | 0.73 | RAB9A (0.79) | RAB9APOLBL3MBTL1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472959-A1 | SMO MODULATOR COMPOUNDS | Omass Therapeutics Limited (GB) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023148481-A1 | SMO MODULATOR COMPOUNDS | Omass Therapeutics Limited (GB) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023148481-A1 | SMO MODULATOR COMPOUNDS | Omass Therapeutics Limited (GB) | 2023-08-10 | — | — | WO | disclosed |