Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 17/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PCK1 | P35558 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837752 | 0.93 | ADORA2B (0.44) | ADORA2BADORA1ADORA3ADORA2APCK1 | |
| SCHEMBL835048 | 0.93 | ADORA2B (0.39) | ADORA2BADORA1ADORA3ADORA2APCK1 | |
| SCHEMBL874355 | 0.92 | ADORA2B (0.44) | ADORA2BADORA1ADORA3ADORA2APCK1 | |
| SCHEMBL837291 | 0.92 | ADORA2B (0.48) | ADORA2BADORA1ADORA3ADORA2A | |
| SCHEMBL837154 | 0.92 | ADORA2B (0.43) | ADORA2BADORA1ADORA3ADORA2APCK1 | |
| SCHEMBL834086 | 0.92 | ADORA2B (0.39) | ADORA2BADORA1ADORA3ADORA2APCK1 | |
| SCHEMBL836299 | 0.92 | ADORA2B (0.39) | ADORA2BADORA1ADORA3ADORA2APCK1 | |
| SCHEMBL838372 | 0.91 | ADORA2B (0.38) | ADORA2BADORA1ADORA3ADORA2APCK1 | |
| SCHEMBL835128 | 0.91 | ADORA2B (0.38) | ADORA2BADORA1ADORA3ADORA2APCK1 | |
| SCHEMBL3115332 | 0.91 | ADORA2B (0.40) | ADORA2BADORA1ADORA3ADORA2APCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110257205-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | GLAXOSMITHKLINE LLC | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257205-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | GPR84, GPR88, XDH | ADORA2B 97/4885ADORA1 24/4885ADORA3 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.