Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.32 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30521137 | 1.00 | ACHE (0.38) | ACHEKCNH2CCR3DRD2DRD1 | |
| SCHEMBL25343022 | 0.93 | ACHE (0.37) | ACHEKCNH2CCR3DRD2DRD1 | |
| SCHEMBL30520877 | 0.86 | ALDH1A1 (0.39) | ACHEKCNH2DRD2DRD1KDM4E | |
| SCHEMBL25341098 | 0.85 | POLB (0.47) | ALDH1A1HPGDPOLBIDO1TDO2 | |
| SCHEMBL25341816 | 0.83 | ALDH1A1 (0.35) | ACHEKCNH2DRD2DRD1KDM4E | |
| SCHEMBL30521235 | 0.80 | ACHE (0.34) | ACHEKCNH2KDM4EALDH1A1LMNA | |
| SCHEMBL25344204 | 0.80 | KCNH2 (0.38) | ACHEKCNH2DRD2DRD1KDM4E | |
| SCHEMBL25343824 | 0.80 | ACHE (0.34) | ACHEKCNH2KDM4EALDH1A1LMNA | |
| SCHEMBL25342753 | 0.76 | ACHE (0.37) | ACHEKCNH2DRD2DRD1KDM4E | |
| SCHEMBL30521077 | 0.76 | ACHE (0.37) | ACHEKCNH2DRD2DRD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143494-A1 | NEW PROTAC COMPOUND | 甘李药业股份有限公司 | 2023-08-03 | — | — | WO | disclosed |