Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25343022 | 0.90 | ACHE (0.37) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL25341098 | 0.86 | POLB (0.47) | ALDH1A1HPGDPOLBIDO1TDO2 | |
| SCHEMBL30521137 | 0.86 | ACHE (0.38) | ALDH1A1KDM4ELMNAHPGDDRD2 | |
| SCHEMBL25341745 | 0.86 | ACHE (0.38) | ALDH1A1KDM4ELMNAHPGDDRD2 | |
| SCHEMBL30521537 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL25342588 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL30521077 | 0.76 | ACHE (0.37) | ALDH1A1KDM4EMAPTDRD2DRD1 | |
| SCHEMBL25342753 | 0.76 | ACHE (0.37) | ALDH1A1KDM4EMAPTDRD2DRD1 | |
| SCHEMBL25341816 | 0.75 | ALDH1A1 (0.35) | ALDH1A1KDM4ELMNAMAPTHPGD | |
| SCHEMBL25343824 | 0.74 | ACHE (0.34) | ALDH1A1KDM4ELMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574822-A | Novel PROTAC compounds | 甘李药业股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023143494-A1 | NEW PROTAC COMPOUND | 甘李药业股份有限公司 | 2023-08-03 | — | — | WO | disclosed |