SCHEMBL2534281

SCHEMBL2534281

O=C(O)c1cc(-c2cccc3ccccc23)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 9/20 1.00
ACMSD Q8TDX5 7/20 1.00
DHFR P00374 1/20 0.60
HNF4A P41235 1/20 0.60
LCK P06239 2/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
NR4A1 P22736 1/20 0.51
NR4A2 P43354 1/20 0.51
NR4A3 Q92570 1/20 0.51
XDH P47989 1/20 0.51
SLC22A12 Q96S37 1/20 0.51
ALDH1A1 P00352 1/20 0.51
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9534579 0.88 MCL1 (0.78) MCL1ACMSDHNF4AMEN1KMT2A
SCHEMBL12892157 0.85 MCL1 (0.74) MCL1ACMSDMEN1KMT2ANR4A1
SCHEMBL17202660 0.85 MCL1 (0.77) MCL1ACMSDDHFRHNF4ALCK
SCHEMBL5494830 0.83 MCL1 (0.71) MCL1ACMSDMEN1KMT2AHTT
SCHEMBL28410866 0.83 MCL1 (0.70) MCL1ACMSDMEN1KMT2ANR4A1
SCHEMBL2533617 0.82 ACMSD (0.76) MCL1ACMSDDHFRHNF4ALCK
SCHEMBL29744510 0.80 APP (0.67) MCL1ACMSD
SCHEMBL28350260 0.80 APP (0.67) MCL1ACMSD
SCHEMBL20961998 0.78 MCL1 (0.64) MCL1ACMSDDHFRHNF4AXDH
SCHEMBL11782188 0.78 MCL1 (0.64) MCL1ACMSDMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250162979-A1 P-DIPHENYL COMPOUND DERIVATIVE MIXTURE AND METHOD OF PRODUCING THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2025-05-22 US disclosed
US-20220324791-A1 P-DIPHENYL COMPOUND DERIVATIVE MIXTURE AND METHOD OF PRODUCING THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2022-10-13 US disclosed
EP-2394980-B1 AROMATIC AMINO COMPOUND MANUFACTURING METHOD HODOGAYA CHEMICAL CO LTD (JP) 2016-12-21 EP disclosed
US-9238624-B2 Method of producing aromatic amino compounds HODOGAYA CHEMICAL CO., LTD. (JP) 2016-01-19 US disclosed
US-20140163232-A1 METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS HODOGAYA CHEMICAL CO., LTD. (JP) 2014-06-12 US disclosed
US-8735626-B2 Method of producing aromatic amino compounds HODOGAYA CHEMICAL CO., LTD. (JP) 2014-05-27 US disclosed
EP-2394980-A1 AROMATIC AMINO COMPOUND MANUFACTURING METHOD Hodogaya Chemical Co., Ltd. (JP) 2011-12-14 EP disclosed
CN-102239133-A Aromatic amino compound manufacturing method HODOGAYA CHEMICAL CO LTD 2011-11-09 CN disclosed
US-20110257404-A1 METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS HODOGAYA CHEMICAL CO., LTD. (JP) 2011-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220324791-A1 P-DIPHENYL COMPOUND DERIVATIVE MIXTURE AND METHOD OF PRODUCING THE SAME DDT, CYP2D6, CYP3A4 MCL1 711/4885ACMSD 692/4885DHFR 53/4885
US-20140163232-A1 METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS DDC, AOC2, AOC3 MCL1 3218/4885ACMSD 43/4885DHFR 127/4885
US-20110257404-A1 METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS AOC2, AOC3, DDC MCL1 2994/4885ACMSD 63/4885DHFR 1149/4885
US-20250162979-A1 P-DIPHENYL COMPOUND DERIVATIVE MIXTURE AND METHOD OF PRODUCING THE SAME DDT, CYP2D6, CYP3A4 MCL1 711/4885ACMSD 692/4885DHFR 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.