Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.71 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.71 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534281 | 0.83 | MCL1 (1.00) | MCL1ACMSDMEN1KMT2AHTT | |
| SCHEMBL5486902 | 0.81 | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 (0.63) | MCL1TMPRSS4MEN1KMT2AKDM4E | |
| SCHEMBL6282455 | 0.80 | TMPRSS4 (0.67) | MCL1ACMSDTMPRSS4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7207139 | 0.80 | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 (0.62) | MCL1TMPRSS4MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7207137 | 0.79 | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 (0.60) | MCL1TMPRSS4MEN1KMT2AKDM4E | |
| SCHEMBL5491008 | 0.78 | DEGS1 (0.60) | MEN1KMT2AKDM4ELMNATP53 | |
| SCHEMBL25270298 | 0.75 | KDM4E (0.67) | ACMSDTMPRSS4MEN1KMT2AKDM4E | |
| SCHEMBL368228 | 0.75 | DEGS1 (0.78) | MEN1KMT2AKDM4ELMNATP53 | |
| SCHEMBL31150345 | 0.75 | DEGS1 (0.78) | MEN1KMT2AKDM4ELMNATP53 | |
| SCHEMBL9534579 | 0.75 | MCL1 (0.78) | MCL1ACMSDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328507-B1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | UNIV NEW YORK STATE RES FOUND (US) | 2007-03-14 | — | — | EP | disclosed |
| US-6960553-B2 | Heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20030186810-A1 | Heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD. | 2003-10-02 | — | — | US | disclosed |
| EP-1328507-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | The Research Foundation Of State University of New York (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6407288-B1 | AS ANTIBACTERIAL AGAINST GRAM NEGATIVE AND GRAM POSITIVE BACTERIA AND AS ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-06-18 | — | — | US | disclosed |
| US-20020065322-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | 2002-05-30 | — | — | US | disclosed |
| WO-2002028819-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065322-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | PTGES3, FPR3, PTGS1 | MCL1 615/4885ACMSD 1707/4885TMPRSS4 2731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.