Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118129 | 0.72 | ALDH1A1 (0.46) | CYP3A4ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL9718917 | 0.72 | CYP2A6 (0.40) | TSHRALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL5918765 | 0.72 | IDO1 (0.35) | — | |
| SCHEMBL498541 | 0.72 | ALDH1A1 (0.40) | CYP3A4ALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL29412287 | 0.71 | ESR2 (0.60) | ESR2GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL222 | 0.71 | ESR2 (0.60) | ESR2GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21174848 | 0.68 | ALDH1A1 (0.41) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL10570890 | 0.68 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MAPK1HPGDLMNA | |
| SCHEMBL6394393 | 0.68 | MAPT (0.36) | ALDH1A1HSD17B10MAPK1HPGDUSP2 | |
| SCHEMBL2520450 | 0.68 | HSD11B1 (0.42) | TSHRTRPA1CYP1A2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670217-B2 | Process for preparing chlorins and their pharmaceutical uses | UNIVERSIDADE DE COIMBRA (PT) | 2017-06-06 | — | — | US | disclosed |
| EP-2346874-B1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | UNIV DE COIMBRA (PT) | 2013-12-04 | — | — | EP | disclosed |
| US-20110250143-A1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | UNIVERSIDADE DE COIMBRA (PT) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110250143-A1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | CD68, HMBS, MKI67 | ESR2 3100/4885GABRG2 2682/4885GABRB3 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.