Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918765 | 0.76 | IDO1 (0.35) | — | |
| SCHEMBL3118129 | 0.72 | ALDH1A1 (0.46) | CYP3A4ALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL9718917 | 0.72 | CYP2A6 (0.40) | HSD11B1NOTUMBACE1ALDH1A1HSD17B10 | |
| SCHEMBL197671 | 0.71 | HSD11B1 (0.56) | HSD11B1NOTUMCYP3A4CYP1A2PSMB8 | |
| SCHEMBL8022901 | 0.69 | HSD11B1 (0.54) | HSD11B1NOTUMCYP3A4CYP1A2PSMB8 | |
| Hydrochloric Acid SCHEMBL29010139 | 0.69 | HSD11B1 (0.54) | HSD11B1NOTUMCYP3A4CYP1A2PSMB8 | |
| SCHEMBL6394393 | 0.68 | MAPT (0.36) | ALDH1A1MAPK1HSD17B10TDP1HPGD | |
| SCHEMBL21174848 | 0.68 | ALDH1A1 (0.41) | CYP3A4ALDH1A1ALOX15HSD17B10TSHR | |
| SCHEMBL2534712 | 0.68 | ESR2 (0.41) | CYP3A4CYP1A2TRPA1ALDH1A1MAPK1 | |
| SCHEMBL10570890 | 0.68 | ALDH1A1 (0.44) | ALDH1A1MAPK1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670217-B2 | Process for preparing chlorins and their pharmaceutical uses | UNIVERSIDADE DE COIMBRA (PT) | 2017-06-06 | — | — | US | disclosed |
| EP-2346874-B1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | UNIV DE COIMBRA (PT) | 2013-12-04 | — | — | EP | disclosed |
| US-20110250143-A1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | UNIVERSIDADE DE COIMBRA (PT) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110250143-A1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | CD68, HMBS, MKI67 | HSD11B1 4484/4885NOTUM 3134/4885CYP3A4 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.