Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4278876 | 0.77 | CETP (0.48) | MAPTTDP1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL498541 | 0.72 | ALDH1A1 (0.40) | MAPTTDP1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL3118129 | 0.72 | ALDH1A1 (0.46) | MAPTTDP1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL5918765 | 0.72 | IDO1 (0.35) | — | |
| SCHEMBL9718917 | 0.72 | CYP2A6 (0.40) | TDP1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL22089472 | 0.72 | RAB9A (0.50) | MAPTL3MBTL1RAB9ASMN1; SMN2POLB | |
| SCHEMBL10779615 | 0.72 | TACR1 (0.38) | MAPTPOLBUSP2ALDH1A1NPSR1 | |
| SCHEMBL10570890 | 0.71 | ALDH1A1 (0.44) | L3MBTL1RAB9ASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL8927888 | 0.71 | MAPT (0.52) | MAPTTDP1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL26977738 | 0.69 | HDAC1 (0.47) | KDM4EPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130189347-A1 | DISEASE TREATMENT DRUG | YUASA MAKOTO (JP) | 2013-07-25 | — | — | US | disclosed |
| EP-2601954-A1 | THERAPEUTIC AGENT FOR DISEASE | Yuasa, Makoto (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-20050008687-A1 | Metal-porphyrin-complex-embedded liposomes, production process thereof, and medicines making use of the same | MAKOTO YUASA (JP) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130189347-A1 | DISEASE TREATMENT DRUG | PPOX, TFRC, SLC40A1 | MAPT 500/4885TDP1 3834/4885L3MBTL1 1564/4885 |
| US-20050008687-A1 | Metal-porphyrin-complex-embedded liposomes, production process thereof, and medicines making use of the same | GPX4, FECH, PPOX | MAPT 3457/4885TDP1 4752/4885L3MBTL1 1923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.