Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739980 | 0.84 | ROCK2 (0.47) | ROCK2MAOAMAOBRAB9ANR3C1 | |
| SCHEMBL18661406 | 0.83 | ROCK2 (0.46) | ROCK2MAOAMAOBRAB9AHDAC1 | |
| SCHEMBL31607389 | 0.83 | ROCK2 (0.46) | ROCK2MAOAMAOBRAB9AHDAC1 | |
| SCHEMBL30088006 | 0.79 | XDH (0.46) | ROCK2MAOAMAOBESR1GRM5 | |
| SCHEMBL28601707 | 0.79 | XDH (0.46) | ROCK2MAOAMAOBESR1GRM5 | |
| SCHEMBL6091339 | 0.77 | NR3C1 (0.57) | ROCK2NR3C1PGRNR3C2AR | |
| SCHEMBL31456523 | 0.77 | NR3C1 (0.57) | ROCK2NR3C1PGRNR3C2AR | |
| SCHEMBL21805739 | 0.76 | ROCK2 (0.40) | ROCK2MAOAMAOBRAB9ANPC1 | |
| SCHEMBL25350212 | 0.73 | AHR (0.39) | RAB9ANR3C1PGRNR3C2AR | |
| SCHEMBL571870 | 0.71 | CA1 (0.44) | ROCK2RAB9AHDAC1HDAC6NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731939-B1 | Indole-based chalcone compounds as antibacterial agents | King Faisal University (SA) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731939-B1 | Indole-based chalcone compounds as antibacterial agents | TPH1, TOP2B, POLB | ROCK2 1943/4885MAOA 229/4885MAOB 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.