Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IL6 | P05231 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478065 | 0.87 | OPRM1 (0.42) | THRBKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL25355807 | 0.85 | THRB (0.42) | THRBKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL31579716 | 0.83 | KDM4E (0.53) | THRBKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL8688804 | 0.81 | MEN1 (0.46) | LTA4HTHRBKDM4ERAB9ANPC1 | |
| SCHEMBL5942883 | 0.81 | OPRM1 (0.47) | LTA4HKDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL8009375 | 0.80 | LIPE (0.48) | LTA4HOPRM1OPRD1OPRK1RAB9A | |
| SCHEMBL17050458 | 0.78 | RAB9A (0.49) | LTA4HTHRBKDM4ERAB9ANPC1 | |
| SCHEMBL5942714 | 0.77 | LTA4H (0.46) | LTA4HTHRBKDM4EOPRM1OPRD1 | |
| SCHEMBL8332212 | 0.77 | KDM4E (0.58) | THRBKDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL8688799 | 0.77 | THRB (0.44) | THRBKDM4ERAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |