Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.71 |
| ▸ | NOS1 | P29475 | 4/20 | 0.71 |
| ▸ | NOS2 | P35228 | 4/20 | 0.71 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.53 |
| ▸ | TPH1 | P17752 | 5/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25357465 | 1.00 | NOS3 (0.71) | NOS3NOS1NOS2ITGB3ITGAV | |
| SCHEMBL23097539 | 0.86 | NOS3 (0.54) | NOS3NOS1NOS2ITGB3ITGAV | |
| SCHEMBL1932906 | 0.83 | SLC7A5 (0.61) | NOS3NOS1NOS2ITGB3ITGAV | |
| SCHEMBL169646 | 0.83 | SLC7A5 (0.61) | NOS3NOS1NOS2ITGB3ITGAV | |
| SCHEMBL169645 | 0.83 | SLC7A5 (0.61) | NOS3NOS1NOS2ITGB3ITGAV | |
| SCHEMBL3059437 | 0.83 | SLC7A5 (0.61) | NOS3NOS1NOS2ITGB3ITGAV | |
| SCHEMBL4943107 | 0.83 | SLC7A5 (0.61) | NOS3NOS1NOS2ITGB3ITGAV | |
| SCHEMBL30037334 | 0.83 | SLC7A5 (0.61) | NOS3NOS1NOS2ITGB3ITGAV | |
| SCHEMBL7240772 | 0.81 | ITGB3 (0.49) | NOS3NOS1NOS2ITGB3ITGAV | |
| SCHEMBL180331 | 0.80 | SLC7A5 (0.57) | NOS3NOS1NOS2ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | claimed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | NOS3 1214/4885NOS1 1488/4885NOS2 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.