Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 3/20 | 0.49 |
| ▸ | NOS1 | P29475 | 3/20 | 0.49 |
| ▸ | NOS2 | P35228 | 3/20 | 0.49 |
| ▸ | TPH1 | P17752 | 4/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6678238 | 0.99 | ITGB3 (0.48) | ITGB3ITGAVITGA2BNOS3NOS1 | |
| SCHEMBL6676210 | 0.86 | ALDH1A1 (0.53) | ITGB3ITGAVITGA2BNOS3NOS1 | |
| SCHEMBL5712137 | 0.82 | DPP7 (0.41) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6754491 | 0.81 | DPP7 (0.41) | ALDH1A1 | |
| SCHEMBL25357465 | 0.81 | NOS3 (0.71) | ITGB3ITGAVITGA2BNOS3NOS1 | |
| SCHEMBL8854032 | 0.81 | KMT2A (0.48) | ALDH1A1SMN1; SMN2TDP1KDM4EMEN1 | |
| SCHEMBL25357459 | 0.81 | NOS3 (0.71) | ITGB3ITGAVITGA2BNOS3NOS1 | |
| SCHEMBL6676200 | 0.79 | LOXL2 (0.44) | ADRA2A | |
| SCHEMBL23097539 | 0.78 | NOS3 (0.54) | ITGB3ITGAVITGA2BNOS3NOS1 | |
| SCHEMBL1932906 | 0.78 | SLC7A5 (0.61) | ITGB3ITGAVITGA2BNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | claimed |