Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25363954 | 0.88 | SIRT1 (0.34) | SIRT1SIRT2SIRT5SIRT3 | |
| SCHEMBL26111048 | 0.85 | NMT2 (0.37) | SIRT1SIRT2SIRT5SIRT3 | |
| SCHEMBL26111054 | 0.85 | NMT2 (0.37) | SIRT1SIRT2SIRT5SIRT3 | |
| SCHEMBL26528591 | 0.79 | CA1 (0.42) | HDAC1CA1CA2SIRT5HDAC4 | |
| SCHEMBL28872431 | 0.73 | NMT2 (0.34) | HDAC1HDAC4MEF2D | |
| SCHEMBL26109642 | 0.72 | NMT2 (0.35) | HDAC1HDAC4MEF2D | |
| SCHEMBL26109645 | 0.72 | NMT2 (0.35) | HDAC1HDAC4MEF2D | |
| SCHEMBL22698709 | 0.65 | NPY4R (0.44) | HDAC1SIRT5 | |
| SCHEMBL27410339 | 0.64 | CA1 (0.51) | SIRT1SIRT2HDAC1CA1CA2 | |
| SCHEMBL24872282 | 0.64 | FURIN (0.39) | HDAC1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155808-A1 | CONJUGATE OF ANTIBODY-ERIBULIN OR DERIVATIVE THEREOF, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 苏州宜联生物医药有限公司 | 2023-08-24 | — | — | WO | disclosed |