Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23541422 | 0.93 | ALDH1A1 (0.33) | ALDH1A1MAPK1KMT2ATDP1L3MBTL1 | |
| SCHEMBL12252543 | 0.88 | KMT2A (0.31) | KMT2A | |
| SCHEMBL20390451 | 0.85 | CYP4F2 (0.36) | ALDH1A1MAPK1KMT2ATDP1 | |
| SCHEMBL6301516 | 0.82 | L3MBTL1 (0.33) | ALDH1A1MAPK1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6889106 | 0.82 | L3MBTL1 (0.33) | ALDH1A1MAPK1KMT2ATDP1L3MBTL1 | |
| SCHEMBL26879455 | 0.81 | — | — | |
| SCHEMBL6301520 | 0.81 | L3MBTL1 (0.33) | ALDH1A1MAPK1KMT2ATDP1L3MBTL1 | |
| SCHEMBL10090479 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MAPK1KMT2ATDP1L3MBTL1 | |
| SCHEMBL2005244 | 0.79 | LMNA (0.41) | KMT2ATDP1 | |
| SCHEMBL2543739 | 0.78 | DPP8 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044203-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| EP-2258776-A1 | Fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2010-12-08 | — | — | EP | disclosed |
| US-20100267008-A1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2010-10-21 | — | — | US | disclosed |
| US-7615646-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-10 | — | — | US | disclosed |
| US-20060051758-A1 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-03-09 | — | — | US | disclosed |
| EP-1525265-A4 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | UNIV CARNEGIE MELLON (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1525265-A2 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE-MELLON UNIVERSITY (US) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004039894-A2 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060051758-A1 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | IDO1, TDO2, IDO2 | ALDH1A1 1689/4885MAPK1 2515/4885KMT2A 1112/4885 |
| US-20100267008-A1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | IDO1, IDO2, INMT | ALDH1A1 1629/4885MAPK1 2128/4885KMT2A 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.