Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31148302 | 0.82 | AKR1B1 (0.39) | AKR1B1SMN1; SMN2TAAR1KMT2AADRA2A | |
| SCHEMBL6889503 | 0.82 | AKR1B1 (0.39) | AKR1B1SMN1; SMN2TAAR1KMT2AADRA2A | |
| SCHEMBL25360558 | 0.82 | AKR1B1 (0.39) | AKR1B1SMN1; SMN2TAAR1KMT2AADRA2A | |
| SCHEMBL11236505 | 0.79 | CYP3A4 (0.47) | AKR1B1SMN1; SMN2TAAR1KMT2AADRA2A | |
| SCHEMBL25368225 | 0.78 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL1007397 | 0.77 | TAAR1 (0.52) | AKR1B1SMN1; SMN2TAAR1KMT2AADRA2A | |
| SCHEMBL5042264 | 0.74 | TAAR1 (0.50) | AKR1B1SMN1; SMN2TAAR1KMT2AADRA2A | |
| Ammonia Solution, Strong SCHEMBL28327987 | 0.74 | TAAR1 (0.50) | AKR1B1SMN1; SMN2TAAR1KMT2AADRA2A | |
| SCHEMBL11029627 | 0.74 | TAAR1 (0.50) | AKR1B1SMN1; SMN2TAAR1KMT2AADRA2A | |
| SCHEMBL12463823 | 0.73 | S100B (0.47) | TAAR1KMT2ALMNAMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179043-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-06-05 | — | — | US | disclosed |
| US-20250163010-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-05-22 | — | — | US | disclosed |
| US-20250154124-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORP (US) | 2025-05-15 | — | — | US | disclosed |
| CN-118715212-A | Preparation of N- (1-methylcyclopropyl) -2- (3-pyridinyl) -2H-indazole-4-carboxamide and intermediates thereof | FMC公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118715213-A | Process for preparing N- (1-methylcyclopropyl) -2- (3-pyridinyl) -2H-indazole-4-carboxamide and intermediates thereof | FMC公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118679154-A | Preparation of N- (1-methylcyclopropyl) -2- (3-pyridinyl) -2H-indazole-4-carboxamide and intermediates thereof | FMC公司 | 2024-09-20 | — | — | CN | disclosed |
| WO-2023158771-A1 | THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORPORATION (US) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023158769-A1 | PROCESSES FOR THE PREPARATION OF N-(1- METHYLCYCLOPROPYL)-2-(3 -PYRIDINYL)-2H- INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORPORATION (US) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023158770-A1 | THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | FMC CORPORATION (US) | 2023-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179043-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | ACHE, CYP4B1, CYP3A4 | AKR1B1 2995/4885SMN1; SMN2 546/4885TAAR1 1807/4885 |
| US-20250154124-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | ACHE, CYP4B1, CYP3A4 | AKR1B1 2995/4885SMN1; SMN2 546/4885TAAR1 1807/4885 |
| US-20250163010-A1 | PROCESSES FOR THE PREPARATION OF N-(1-METHYLCYCLOPROPYL)-2-(3-PYRIDINYL)-2H-INDAZOLE-4-CARBOXAMIDE AND INTERMEDIATES THEREOF | ACHE, CYP4B1, CYP3A4 | AKR1B1 2995/4885SMN1; SMN2 546/4885TAAR1 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.