Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 16/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375801 | 0.77 | BCAT2 (0.42) | PDK2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL22443382 | 0.77 | PDK2 (0.51) | PDK2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL28197969 | 0.70 | LMNA (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL30293277 | 0.67 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3840448 | 0.67 | KDM4E (0.45) | PDK2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11233815 | 0.66 | METAP2 (0.39) | PDK2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL13128010 | 0.66 | PDK2 (1.00) | PDK2 | |
| SCHEMBL39118 | 0.65 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL4967588 | 0.65 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL27700719 | 0.65 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3796975-B1 | SULFONYLAMINOBENZAMIDE DERIVATIVES | ORSOBIO INC (US) | 2023-08-30 | — | — | EP | disclosed |