Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934551 | 0.92 | ALDH1A1 (0.42) | LMNAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5475249 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL28477742 | 0.81 | KDM4E (0.43) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL27966846 | 0.81 | ALDH1A1 (0.52) | LMNAALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL11233815 | 0.81 | METAP2 (0.39) | LMNAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL27944464 | 0.80 | P2RX7 (0.42) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL11119681 | 0.80 | METAP2 (0.38) | LMNAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3823755 | 0.80 | KDM4E (0.43) | LMNAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL31373806 | 0.77 | LMNA (0.45) | LMNAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL31490948 | 0.77 | ALDH1A1 (0.48) | LMNAALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024882-A1 | FLUORINATED ADAMANTYL P2X7 RECEPTOR ANTAGONISTS AND USES THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2025-02-06 | — | — | WO | disclosed |
| WO-2025024881-A1 | ADAMANTYL P2X7 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF CARDIOVASCULAR DISEASES | THE UNIVERSITY OF SYDNEY (AU) | 2025-02-06 | — | — | WO | disclosed |
| WO-2023092175-A1 | NOVEL P2X7 RECEPTOR ANTAGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2023-06-01 | — | — | WO | disclosed |
| CN-107667088-A | NOVEL BENZOIC ACID AMIDE COMPOUND | 株式会社爱茉莉太平洋 | 2018-02-06 | — | — | CN | disclosed |