SCHEMBL25377303

SCHEMBL25377303

Cc1ccc(C(NCCCCC(NC(=O)C(NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)C)C(=O)Nc2ccc(Cc3cc([N+](=O)[O-])ccc3OC(=O)O)cc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 4/20 0.34
▸ SSTR3 P32745 1/20 0.33
▸ FURIN P09958 4/20 0.33
▸ PSMB1 P20618 1/20 0.31
▸ PSMB5 P28074 1/20 0.31
▸ PDF Q9HBH1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29649430 0.87 SSTR3 (0.36) FOLH1SSTR3FURINPDF
SCHEMBL29589720 0.86 SSTR3 (0.36) FOLH1SSTR3FURINPDF
SCHEMBL29048536 0.85 FURIN (0.37) FOLH1FURIN
SCHEMBL25383060 0.85 FURIN (0.37) FOLH1FURIN
SCHEMBL25361536 0.83 SIRT5 (0.38) FOLH1FURIN
SCHEMBL25361554 0.83 SIRT5 (0.38) FOLH1FURIN
SCHEMBL25361987 0.83 FURIN (0.37) FOLH1FURIN
SCHEMBL25350530 0.83 FURIN (0.35) FURIN
SCHEMBL25361975 0.83 FURIN (0.37) FOLH1FURIN
SCHEMBL25360091 0.82 FURIN (0.36) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4275758-A2 METHODS OF FUNCTIONALIZING NANOPARTICLES Elucida Oncology, Inc. (US) 2023-11-15 — — EP disclosed
US-11744897-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof ELUCIDA ONCOLOGY, INC. (US) 2023-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744897-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof FOLR1, FOLR2, DHFR FOLH1 8/4885SSTR3 1520/4885FURIN 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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