SCHEMBL29589720

SCHEMBL29589720

Cc1ccc(C(NCCCC[C@H](NC(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(C)C)C(=O)Nc2ccc(COC(=O)Oc3ccc([N+](=O)[O-])cc3)cc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SSTR3 P32745 1/20 0.36
▸ FURIN P09958 4/20 0.35
▸ HTR2A P28223 1/20 0.35
▸ FOLH1 Q04609 1/20 0.34
▸ SIRT2 Q8IXJ6 4/20 0.33
▸ SIRT1 Q96EB6 4/20 0.33
▸ ELANE P08246 1/20 0.33
▸ SIRT5 Q9NXA8 1/20 0.32
▸ ST6GAL1 P15907 4/20 0.32
▸ PDF Q9HBH1 1/20 0.32
▸ SIRT3 Q9NTG7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29649430 0.95 SSTR3 (0.36) SSTR3FURINFOLH1SIRT2SIRT1
SCHEMBL29649549 0.93 SSTR3 (0.42) SSTR3HTR2AFOLH1SIRT2SIRT1
SCHEMBL26015675 0.89 HTR2A (0.40) SSTR3FURINHTR2AFOLH1SIRT2
SCHEMBL25377303 0.86 FOLH1 (0.34) SSTR3FURINFOLH1PDF
SCHEMBL29649584 0.86 FOLH1 (0.40) SSTR3FOLH1
SCHEMBL25383060 0.86 FURIN (0.37) FURINFOLH1SIRT2SIRT1SIRT5
SCHEMBL29048536 0.86 FURIN (0.37) FURINFOLH1SIRT2SIRT1SIRT5
SCHEMBL25361536 0.86 SIRT5 (0.38) FURINFOLH1SIRT2SIRT1SIRT5
SCHEMBL25361554 0.86 SIRT5 (0.38) FURINFOLH1SIRT2SIRT1SIRT5
SCHEMBL17490581 0.85 HTR2A (0.39) SSTR3FURINHTR2AFOLH1PDF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11957760-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof ELUCIDA ONCOLOGY, INC. (US) 2024-04-16 — — US disclosed
EP-4275758-A2 METHODS OF FUNCTIONALIZING NANOPARTICLES Elucida Oncology, Inc. (US) 2023-11-15 — — EP disclosed
EP-4257156-A2 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF Elucida Oncology, Inc. (US) 2023-10-11 — — EP disclosed
EP-4237008-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF Elucida Oncology, Inc. (US) 2023-09-06 — — EP disclosed
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-24 — — US disclosed
US-20230263899-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-24 — — US disclosed
EP-4103236-B1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY INC (US) 2023-08-16 — — EP disclosed
EP-4106820-B1 METHODS OF FUNCTIONALIZING NANOPARTICLES ELUCIDA ONCOLOGY INC (US) 2023-08-16 — — EP disclosed
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed
US-20230021059-A1 METHODS OF FUNCTIONALIZING NANOPARTICLES ELUCIDA ONCOLOGY, INC. 2023-01-19 — — US disclosed
EP-4106820-A1 METHODS OF FUNCTIONALIZING NANOPARTICLES Elucida Oncology, Inc. (US) 2022-12-28 — — EP disclosed
EP-4103236-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF Elucida Oncology, Inc. (US) 2022-12-21 — — EP disclosed
US-20220378924-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2022-12-01 — — US disclosed
WO-2022093794-A9 METHODS OF FUNCTIONALIZING NANOPARTICLES ELUCIDA ONCOLOGY, INC. (US) 2022-06-09 — — WO disclosed
WO-2022093793-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed
WO-2022093794-A1 METHODS OF FUNCTIONALIZING NANOPARTICLES ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed
WO-2022093800-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220378924-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR SSTR3 1520/4885FURIN 2202/4885HTR2A 2703/4885
US-11957760-B2 Folate receptor targeted nanoparticle drug conjugates and uses thereof FOLR1, FOLR2, DHFR SSTR3 1520/4885FURIN 2202/4885HTR2A 2703/4885
US-20230263899-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR SSTR3 1520/4885FURIN 2202/4885HTR2A 2703/4885
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP SSTR3 3591/4885FURIN 2087/4885HTR2A 4236/4885
US-20230263898-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF FOLR1, FOLR2, DHFR SSTR3 1520/4885FURIN 2202/4885HTR2A 2703/4885
US-20230021059-A1 METHODS OF FUNCTIONALIZING NANOPARTICLES NDC1, NCL, CD47 SSTR3 4332/4885FURIN 1409/4885HTR2A 4689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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