Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30183714 | 0.87 | ALDH1A1 (0.43) | PLK1SIRT6KDM4EKMT2APOLB | |
| SCHEMBL23590845 | 0.87 | ALDH1A1 (0.43) | PLK1SIRT6KDM4EKMT2APOLB | |
| SCHEMBL29267734 | 0.84 | TSHR (0.44) | PLK1SIRT6KDM4EKMT2APOLB | |
| SCHEMBL30183974 | 0.84 | KDM4E (0.39) | PLK1SIRT6KDM4EKMT2APOLB | |
| SCHEMBL25387698 | 0.83 | KDM4E (0.48) | PLK1KDM4EKMT2AMAPTGAA | |
| SCHEMBL23577603 | 0.82 | MAPT (0.45) | SIRT6KDM4EKMT2APOLBMAPT | |
| SCHEMBL30183808 | 0.80 | MAPT (0.36) | PLK1SIRT6KDM4EKMT2APOLB | |
| SCHEMBL30036494 | 0.80 | MAPT (0.36) | PLK1SIRT6KDM4EKMT2APOLB | |
| SCHEMBL17934416 | 0.79 | EGFR (0.46) | KDM4EMAPTALDH1A1 | |
| SCHEMBL29010945 | 0.77 | SIRT6 (0.45) | SIRT6KDM4EKMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165438-A1 | TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-09-07 | — | — | WO | disclosed |