Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30036494 | 1.00 | MAPT (0.36) | MAPTKMT2AKDM4EPOLBRECQL | |
| SCHEMBL30183974 | 0.91 | KDM4E (0.39) | MAPTKMT2AKDM4EPOLBRECQL | |
| SCHEMBL23577643 | 0.89 | TSHR (0.36) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL23590651 | 0.86 | ALDH1A1 (0.46) | KMT2AKDM4EALDH1A1MEN1PLK1 | |
| SCHEMBL30183967 | 0.86 | ALDH1A1 (0.46) | KMT2AKDM4EALDH1A1MEN1PLK1 | |
| SCHEMBL30035755 | 0.86 | ALDH1A1 (0.46) | KMT2AKDM4EALDH1A1MEN1PLK1 | |
| SCHEMBL30183714 | 0.83 | ALDH1A1 (0.43) | MAPTKMT2AKDM4EPOLBRECQL | |
| SCHEMBL23590845 | 0.83 | ALDH1A1 (0.43) | MAPTKMT2AKDM4EPOLBRECQL | |
| SCHEMBL29267734 | 0.81 | TSHR (0.44) | MAPTKMT2AKDM4EPOLBRECQL | |
| SCHEMBL25387167 | 0.80 | CTRC (0.38) | MAPTKMT2AKDM4EPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |