SCHEMBL25400667

SCHEMBL25400667

O=C(c1ccccc1)c1cc(Br)c2cc(C(F)(F)F)ccn12

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 7/20 0.47
▸ FNTB P49356 7/20 0.47
▸ SRD5A2 P31213 1/20 0.43
▸ CNR2 P34972 2/20 0.40
▸ ADORA1 P30542 1/20 0.40
▸ CNR1 P21554 1/20 0.39
▸ CES2 O00748 1/20 0.39
▸ GLA P06280 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ LMNA P02545 1/20 0.38
▸ MAT2A P31153 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ TAS2R14 Q9NYV8 1/20 0.37
▸ P2RX1 P51575 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29547648 0.91 SRD5A2 (0.43) FNTAFNTBSRD5A2CES2HPGD
SCHEMBL26300565 0.84 FNTA (0.47) FNTAFNTBSRD5A2CNR2ADORA1
SCHEMBL30676989 0.84 MAPT (0.43) HPGDLMNAMAPT
SCHEMBL26300513 0.82 BACE1 (0.45) FNTAFNTBSRD5A2CNR2CNR1
SCHEMBL29547634 0.82 FNTA (0.54) FNTAFNTBSRD5A2CES2MAPT
SCHEMBL29547156 0.81 L3MBTL1 (0.36) FNTAFNTBHPGDLMNAMAPT
SCHEMBL25399546 0.81 BAZ2B (0.38) HPGDMAT2AMAPT
SCHEMBL26300393 0.80 BACE1 (0.45) FNTAFNTBSRD5A2CNR2MAT2A
SCHEMBL25402450 0.79 FNTA (0.68) FNTAFNTBLMNAMAPT
SCHEMBL29547188 0.79 ALDH1A1 (0.40) FNTAFNTBSRD5A2CES2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-B1 COMPOSITION COMPRISING AN INDOLIZINE DERIVATIVE AND A CYCLIC DINUCLEOTIDE AS ACTIVE AGENTS UNIV AJOU IND ACADEMIC COOP FOUND (KR) 2025-02-12 — — EP disclosed
US-20230390319-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-12-07 — — US disclosed
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
WO-2022086260-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT 아주대학교산학협력단 2022-04-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230390319-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT STING1, IRF3, IFNG FNTA 2708/4885FNTB 2743/4885SRD5A2 1180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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